Structure of PDB 8h5z Chain A

Receptor sequence
>8h5zA (length=559) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAELARLARG
RVLVLAHVKELVAQNHAKYQALGLEADIFAAGHGKVVFGSVQSVARNLDA
FQGEFSLLIVDECHRIGDDSQYQQILTHLTKVNPHLRLLGLTATPFRLGK
GWIYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQ
YDFSRLQAQSNGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIF
AATVEHAKEIVGLLPAEDAALITGDTPGAERDVLIENFKAQRFRYLVNVA
VLTTGFDAPHVDLIAILRPTESVSLYQQIVGRGLRLAPGKTDCLILDYAG
NPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANTFWGKTTADGTLIEHFG
RRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDICDTVLVDPDDMLKAA
LRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERFRLQTPAQ
RTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYW
QVREKVFDY
3D structure
PDB8h5z Biochemical and Structural Analyses Shed Light on the Mechanisms of RadD DNA Binding and Its ATPase from Escherichia coli.
ChainA
Resolution3.00003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS A T4 R6 Q9 P32 T33 G36 K37 L39 K68 R343 T4 R6 Q9 P32 T33 G36 K37 L39 K68 R335
BS02 ZN A C384 C411 C425 C376 C403 C417
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006301 postreplication repair
GO:0006302 double-strand break repair
GO:0006412 translation
GO:0009410 response to xenobiotic stimulus
GO:0010212 response to ionizing radiation
GO:0051301 cell division

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8h5z, PDBe:8h5z, PDBj:8h5z
PDBsum8h5z
PubMed36614183
UniProtP33919|RADD_ECOLI Putative DNA repair helicase RadD (Gene Name=radD)

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