Structure of PDB 8h5y Chain A

Receptor sequence
>8h5yA (length=564) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAELARLARG
RVLVLAHVKELVAQNHAKYQALGLEADIFAAGGKVVFGSVQSVARNLDAF
QGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLG
KGWIYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVV
QYDFSRLQAQSNGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMI
FAATVEHAKEIVGLLPAEDAALITGDTPGAERDVLIENFKAQRFRYLVNV
AVLTTGFDAPHVDLIAILRPTESVSLYQQIVGRGLRLAPGKTDCLILDYA
GNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANTFWGKTTADGTLIEHF
GRRCQGWFEDDDGHREQCDFRFRFKNCQCNAENDIAARRCDTVLVDPDDM
LKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERFRLQ
TPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMK
GQYWQVREKVFDYE
3D structure
PDB8h5y Biochemical and Structural Analyses Shed Light on the Mechanisms of RadD DNA Binding and Its ATPase from Escherichia coli.
ChainA
Resolution2.7001 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C384 C387 C411 C425 C377 C380 C404 C418
BS02 ADP A T4 R6 Q9 T33 G34 G36 K37 L39 K68 R343 T4 R6 Q9 T33 G34 G36 K37 L39 K68 R336
BS03 MG A G36 K37 S38 G36 K37 S38
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003697 single-stranded DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006301 postreplication repair
GO:0006302 double-strand break repair
GO:0006412 translation
GO:0009410 response to xenobiotic stimulus
GO:0010212 response to ionizing radiation
GO:0051301 cell division

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Molecular Function
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Biological Process
External links
PDB RCSB:8h5y, PDBe:8h5y, PDBj:8h5y
PDBsum8h5y
PubMed36614183
UniProtP33919|RADD_ECOLI Putative DNA repair helicase RadD (Gene Name=radD)

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