Structure of PDB 8h3y Chain A

Receptor sequence
>8h3yA (length=348) Species: 817 (Bacteroides fragilis) [Search protein sequence]
VTASIDLQSVSYTDLATQLNDVSDFGKMIILKDNGFNRQVHVSMDKRTKI
QLDNENVRLFNGRDKDSTSFILGDEFAVLRFYRNGESISYIAYKEAQMMN
EIAEFYAAPFKKTRAINEKEAFECIYDSAGKDIVSVKINIDKAKKILNLP
ECDYINDYIKTPAVPSEPKTVYVICLRENGSTIYPNEVSAQMQDAANSVY
AVHGLKRYVNFHFVLYTTEYSCPSGDAKEGLEGFTASLKSNPKAEGYDDQ
IYFLIRWGTWDNKILGMSWFNSYNVNTASDFEASGMSTTQLMYPGVMAHE
LGHILGAEHTDNSKDLMYATFTGYLSHLSEKNMDIIAKNLGWEAADGD
3D structure
PDB8h3y Screening and epitope characterization of diagnostic nanobody against total and activated Bacteroides fragilis toxin.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.74: fragilysin.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A D194 H348 H352 H358 D157 H299 H303 H309
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:8h3y, PDBe:8h3y, PDBj:8h3y
PDBsum8h3y
PubMed36845160
UniProtP54355|ENTM_BACFG Fragilysin (Gene Name=btfP)

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