Structure of PDB 8gzq Chain A

Receptor sequence
>8gzqA (length=852) Species: 12637 (Dengue virus) [Search protein sequence]
ETLGEKWKKRLNQLSRKEFDLYKKSGITEVDRTEAKEGLKRGEITHHAVS
RGSAKLQWFVERNMVIPEGRVIDLGCGRGGWSYYCAGLKKVTEVRGYTKG
GPGHEEPVPMSTYGWNIVKLMSGKDVFYLPPEKCDTLLCDIGESSPSPTV
EESRTIRVLKMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLVR
NPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMTYRRPTIEKDVD
LGAGTRHVNAEPETPNMDVIGERIRRIKEEHSSTWHYDDENPYKTWAYHG
SYEVKASMINGVVKLLTKPWDVVPTVTQMAMTDTTPFGQQRVFKEKVDTR
TPKPMPGTRKVMEITAGWLWRTLGRNKRPRLCTREEFTKKVRTNQWDSAR
AAVEDEEFWKLVDRERELHKQGKCGSCVYNMMRAIWYMWLGARYLEFEAL
GFLNEDHWFSRENSYSGVEGEGLHKLGYILRDISKIPGGAMYADDTAGWD
TRITEDDLHNEEKITQQMDPEHRQLANAIFKLTYQNKVVKVQRPTPKGTV
MDIISRKDQRGSGQVGTYGLNTFTNMEAQLIRQMEGEGVLSKTDLENPHL
LEKKITQWLETKGVERLKRMAISGDDCVVKPIDDRFANALLALNDMGKVR
KDIPQWQPSKGWHDWQQVPFCSHHFHELIMKDGRKLVVPCRPQDELIGRA
RISQGAGWSLKETACLGKAYAQMWALMYFHRRDLRLASNAICSAVPVHWV
PTSRTTWSIHAHHQWMTTEDMLTVWNRVWIEDNPWMEDKTPVTTWEDVPY
LGKREDQWCGSLIGLTSRATWAQNILTAIQQVRSLIGNEEFLDYMPSMKR
FR
3D structure
PDB8gzq Structures of dengue virus RNA replicase complexes.
ChainA
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity
GO:0004482 mRNA 5'-cap (guanine-N7-)-methyltransferase activity
GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
Biological Process
GO:0032259 methylation
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:8gzq, PDBe:8gzq, PDBj:8gzq
PDBsum8gzq
PubMed37478848
UniProtQ5I3C1

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