Structure of PDB 8grz Chain A

Receptor sequence
>8grzA (length=147) Species: 9606 (Homo sapiens) [Search protein sequence]
RPEPELIRQSWRAVSRSPLEHGTVLFARLFALEPDLLPLFQYNCRQFSSP
EDCLSSPEFLDHIRKVMLCIDAAVTNVEDLSSLEEYLASLGRKHRAVGVK
LSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWD
3D structure
PDB8grz X-ray crystal structure of V71C human neuroglobin mutant
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM A F42 H64 K67 V68 C71 L92 K95 H96 V99 F106 V109 F40 H62 K65 V66 C69 L90 K93 H94 V97 F104 V107
Gene Ontology
Molecular Function
GO:0005092 GDP-dissociation inhibitor activity
GO:0005344 oxygen carrier activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0046872 metal ion binding
GO:0098809 nitrite reductase activity
Biological Process
GO:0001666 response to hypoxia
GO:0015671 oxygen transport
GO:0071456 cellular response to hypoxia
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:8grz, PDBe:8grz, PDBj:8grz
PDBsum8grz
PubMed
UniProtQ9NPG2|NGB_HUMAN Neuroglobin (Gene Name=NGB)

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