Structure of PDB 8gpn Chain A

Receptor sequence
>8gpnA (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB8gpn Menin "reads" H3K79me2 mark in a nucleosomal context.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H39 Y41 R42 R72 R83 F84 S86 V117 T118 M120 H3 Y5 R6 R36 R47 F48 S50 V81 T82 M84
BS02 dna A R40 Y41 V46 R63 K64 L65 P66 R69 R4 Y5 V10 R27 K28 L29 P30 R33
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8gpn, PDBe:8gpn, PDBj:8gpn
PDBsum8gpn
PubMed36795828
UniProtP84233|H32_XENLA Histone H3.2

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