Structure of PDB 8gob Chain A

Receptor sequence
>8gobA (length=367) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFAQSTVEK
SFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTA
KALAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMV
IVDTKIVAGAPARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAAL
ALAELCYNTLLEEGEKAMLAAEQHVVTPALERVIEANTYLSGVGFESGGL
AAAHAVHNGLTAIPDAHHYYHGEKVAFGTLTQLVLENAPVEEIETVAALS
HAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGETIHNMPGGATPDQVYA
ALLVADQYGQRFLQEWE
3D structure
PDB8gob Structural and functional insights into the flexible beta-hairpin of glycerol dehydrogenase.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.6: glycerol dehydrogenase.
1.1.1.75: (R)-aminopropanol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D171 H254 H271 D171 H254 H271
BS02 NAD A D37 F39 G93 G94 K95 D98 T116 I117 S119 T120 D121 A122 S125 L127 V129 Y131 A160 D37 F39 G93 G94 K95 D98 T116 I117 S119 T120 D121 A122 S125 L127 V129 Y131 A160
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008888 glycerol dehydrogenase (NAD+) activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0019147 (R)-aminopropanol dehydrogenase activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006071 glycerol metabolic process
GO:0019588 anaerobic glycerol catabolic process
GO:0051289 protein homotetramerization
GO:0051596 methylglyoxal catabolic process
Cellular Component
GO:0005829 cytosol
GO:0032991 protein-containing complex

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Cellular Component
External links
PDB RCSB:8gob, PDBe:8gob, PDBj:8gob
PDBsum8gob
PubMed37165682
UniProtP0A9S5|GLDA_ECOLI Glycerol dehydrogenase (Gene Name=gldA)

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