Structure of PDB 8get Chain A

Receptor sequence
>8getA (length=639) Species: 301301 (Roseburia hominis) [Search protein sequence]
MREVINFNTKWAFTKEATEVPKEMPEKWYWVTLPHSWNEIDGQDGGNDYY
RGTCYYAKQLKKSELPEADCYYLELRGANASADVYVNGKAVAHHDGGYST
WRVDITKELTEEENLIVIAVENGVNDRVYPQNADFTFYGGLYRDVNIIAV
NKSHFDLDYYGGPGIKVTPEIKGADASVEVEVFLTNAADQKLVYTVKDAE
GKEVAKTETAETKAVLSIPAVHLWNGKKDPYLYTAEVALVSGEEAVDAVS
TRFGCRTFEIDPERGFILNGEEYPLRGVSRHQDRWGIGNALLPEHHREDI
DLICELGATTIRLAHYQHDQYFYDLCDERGLVIWAEIPYISSHMPNGREN
TISQMKELVVQNYNHPSIVVWGLSNEITMSSDEDLLENHRILNDMVHEMD
HTRLTTIAVVSMCDIHDPYIQIPDVISYNHYFGWYGGDVSMNGPWMDNFH
KEFPNIPLGMSEYGCEALNWHTSDPKQGDYTEEYQAYYHEEMIKQLFTRK
YIWATHVWNMFDFGADARNEGGENGQNHKGLVTFDRKYKKDSFYAYKAWL
SDEPFVHLCGKRYVDRVEDTTKVTVYSNLPEVELFVNGKSAGKLQAEDHF
FHFEVPNVGESTLVAVAGEYKDESHIRKVDTFNEEYSLK
3D structure
PDB8get Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BDP A D133 H317 E378 Y435 Y439 E466 W512 F517 R522 K533 D134 H315 E376 Y431 Y435 E462 W508 F513 R518 K529
BS02 FMN A D155 Y158 K165 F182 K358 V362 Y365 D156 Y159 K166 F183 K356 V360 Y363
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8get, PDBe:8get, PDBj:8get
PDBsum8get
PubMed38754417
UniProtA0A395V8I7

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