Structure of PDB 8gd3 Chain A

Receptor sequence
>8gd3A (length=343) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
PVWKDADTTLFCASDAKAYETEVHNVWATHACVPTDPNPQEIHLENVTEN
FNMWKNNMVEQMHEDIISLWDQSLQPCVKLTGGSVIKQACPKISFDPIPI
HYCTPAGYVILKCNDKNFNGTGPCKNVSSVQCTHGIKPVVSTQLLLNGSL
AEEEIIIRSENLTNNAKTIIVHLNKSVEINCTRPSNGGDIRKAYCEINGT
KWNKVLKQVTEKLKEHFNNKTIIFQPPSGGDLEITMHSFNCRGEFFYCNT
TQLFNNTCKGCNGTITLPCKIKQIINMWQGTGQAMYAPPIDGKINCVSNI
TGILLTRDGGANNTSNETFRPGGGDMRDNWRSELYKYKVVQIE
3D structure
PDB8gd3 Piperidine CD4-Mimetic Compounds Expose Vulnerable Env Epitopes Sensitizing HIV-1-Infected Cells to ADCC.
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Z1Z A V255 S256 D368 E370 F376 F382 I424 N425 M426 W427 G429 T430 M475 V140 S141 D231 E233 F239 F245 I275 N276 M277 W278 G280 T281 M326
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8gd3, PDBe:8gd3, PDBj:8gd3
PDBsum8gd3
PubMed37243271
UniProtA0A0M3KKW9

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