Structure of PDB 8gbn Chain A

Receptor sequence
>8gbnA (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
SMADFRKFFAKAKHIVIISGAGVSAESGVPTFRGAGGYWRKWQAQDLATP
LAFAHNPSRVWEFYHYRREVMGSKETNAGHRAIAECETRLGKQGRRVVVI
TQNIDELHRKAGTKNLLEIHGSLFKTRCTSCGVVAENYKSPICPALSGKG
APEPGTQDASIPVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRE
LAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTEFRFHFQGPCGT
TLPEALA
3D structure
PDB8gbn Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C166 C169 C207 C212 C128 C131 C169 C174
External links
PDB RCSB:8gbn, PDBe:8gbn, PDBj:8gbn
PDBsum8gbn
PubMed38846003
UniProtQ9NXA8|SIR5_HUMAN NAD-dependent protein deacylase sirtuin-5, mitochondrial (Gene Name=SIRT5)

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