Structure of PDB 8gaf Chain A

Receptor sequence
>8gafA (length=283) Species: 486 (Neisseria lactamica) [Search protein sequence]
TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNNLIDEAHEQENVKGKEKGEKTEAARQY
MCSRYYDIRTFGAVMTTGKNAGQVRGPVQLTFSRSIDPIMTLEHSITRMA
VTNEKDASETGDNRTMGRKFTVPYGLYRCHGFISTHFAKQTGFSENDLEL
FWQALVNMFDHDHSAARGQMNARGLYVFEHSNNLGDAPADSLFKRIQVVK
KDGVEVVRSFDDYLVSVDDKNLEETKLLRKLGG
3D structure
PDB8gaf Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
ChainA
Resolution3.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A N21 G22 D23 D25 T42 V44 K47 R48 R51 G113 A114 V115 Q124 V125 R126 I147 T148 R149 M150 R169 S215 R218 N20 G21 D22 D24 T41 V43 K46 R47 R50 G112 A113 V114 Q123 V124 R125 I146 T147 R148 M149 R168 S214 R217
Gene Ontology
Biological Process
GO:0043571 maintenance of CRISPR repeat elements

View graph for
Biological Process
External links
PDB RCSB:8gaf, PDBe:8gaf, PDBj:8gaf
PDBsum8gaf
PubMed38242128
UniProtD0W8X6

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