Structure of PDB 8g9u Chain A

Receptor sequence

>8g9uA (length=283) Species: 486 (Neisseria lactamica) [Search protein sequence]

TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNNLIDEAHEQENVKGKEKGEKTEAARQY
MCSRYYDIRTFGAVMTTGKNAGQVRGPVQLTFSRSIDPIMTLEHSITRMA
VTNEKDASETGDNRTMGRKFTVPYGLYRCHGFISTHFAKQTGFSENDLEL
FWQALVNMFDHDHSAARGQMNARGLYVFEHSNNLGDAPADSLFKRIQVVK
KDGVEVVRSFDDYLVSVDDKNLEETKLLRKLGG

3D structure

PDB

8g9u Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	A	N21 G22 D25 R31 T42 V44 C45 K47 R48 R51 G113 A114 V115 T117 Q124 V125 R126 Q130 I147 T148 R149 M150 R165 S215 A216 R218	N20 G21 D24 R30 T41 V43 C44 K46 R47 R50 G112 A113 V114 T116 Q123 V124 R125 Q129 I146 T147 R148 M149 R164 S214 A215 R217
BS02	dna	A	N74 V115 T117 T118 S146 R149 T153 N154 K156 R165 T166 M167 G168 R169	N73 V114 T116 T117 S145 R148 T152 N153 K155 R164 T165 M166 G167 R168

Gene Ontology

	Biological Process
GO:0043571	maintenance of CRISPR repeat elements

View graph for
Biological Process

External links

PDB	RCSB:8g9u, PDBe:8g9u, PDBj:8g9u
PDBsum	8g9u
PubMed	38242128
UniProt	D0W8X6

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