Structure of PDB 8g8d Chain A

Receptor sequence
>8g8dA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
QVQLVQSGSELKKPGASVKVSCKASGYTFNNYAMNWVRQAPGQGLEWMGW
INTNTGNPTYGQGFTGRFVFSLDTSVSTAYLQISSLKTEDTAVYYCARFR
VAPAAQRGYFYYYMDVWGKGTTVTVSSASTKGPSVFPLAPSSKSTSGGTA
ALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPS
SSLGTQTYICNVNHKPSNTKVDKKVEPKSC
3D structure
PDB8g8d Vaccine induction of heterologous HIV-1 neutralizing antibody B cell lineages in humans
ChainA
Resolution2.02 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A N30 N31 Y32 A33 W50 N52 T52A N53 R96 V97 G100D Y100E F100F Y100H N30 N31 Y32 A33 W50 N52 T53 N54 R100 V101 G108 Y109 F110 Y112
External links
PDB RCSB:8g8d, PDBe:8g8d, PDBj:8g8d
PDBsum8g8d
PubMed38761800
UniProtP0DOX5|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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