Structure of PDB 8g89 Chain A

Receptor sequence

>8g89A (length=285) Species: 9615 (Canis lupus familiaris) [Search protein sequence]

NIILDLLLLLLTIIYSYLEALVKVFFPRKRKSVAGEIVLITGAGHGIGRW
TAYEFAKQKSRLVLWDINKHGVEETAAECRKLGATVHTFVVDCGNREDIY
NSVKQVKKEVGDVTILVNNAGTVYPADLLSTKDEEITKTFEINILGHFWI
TKALLPSMIKRNHGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTL
ELQTLGITGIKTSCLCPVFVNTGFTKNPSTRLWPILETDTVARSLIDGIL
TNKKMIFVPSYYNIYLILDKFLPERALAAINHLQN

3D structure

PDB

8g89 Structural basis of lipid-droplet localization of 17-beta-hydroxysteroid dehydrogenase 13.

Chain

Resolution

2.222 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	A	G43 H46 G47 I48 D67 I68 V92 D93 C94 N120 A121 G122 I143 S172 Y185 K189 P218 V219 F220 V221 T223 F225	G42 H45 G46 I47 D66 I67 V91 D92 C93 N119 A120 G121 I142 S171 Y184 K188 P217 V218 F219 V220 T222 F224
BS02	YXW	A	S172 C174 I179 P180 Y181 Y185 F220 T226 K227 N286	S171 C173 I178 P179 Y180 Y184 F219 T225 K226 N285

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding

View graph for
Molecular Function

External links

PDB	RCSB:8g89, PDBe:8g89, PDBj:8g89
PDBsum	8g89
PubMed	37620305
UniProt	A0A8I3RYU0

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