Structure of PDB 8g6r Chain A

Receptor sequence
>8g6rA (length=899) Species: 28295 (Porcine epidemic diarrhea virus) [Search protein sequence]
DMAYLNRVRGSSAARLEPCNGTDTQHVYRAFDIYNKDVACLGKFLKVNCV
RLKNLDKHDAFYVVKRCTKSAMEHEQSIYSRLEKCGAVAEHDFFTWKDGR
AIYGNVCRKDLTEYTMMDLCYALRNFDENNCDVLKSILIKVGACEESYFN
NKVWFDPVENEDIHRVYALLGTIVSRAMLKCVKFCDAMVEQGIVGVVTLD
NQDLNGDFYDFGDFTCSIKGMGIPICTSYYSYMMPVMGMTNCLASECFVK
SDIFGEDFKSYDLLEYDFTEHKTALFNKYFKYWGLQYHPNCVDCSDEQCI
VHCANFNTLFSTTIPITAFGPLCRKCWIDGVPLVTTAGYHFKQLGIVWNN
DLNSINELLQFCSDPALLIASSPALVDQRTVCFSVAALGTGMTNQTVKPG
HFNKEFYDFLLEQGFFSEGSELTLKHFFFAQKGDAAVKDFDYYRYNRPTV
LDICQARVVYQIVQRYFDIYEGGCITAKEVVVTNLNKSAGYPLNKFGKAG
LYYESLSYEEQDELYAYTKRNILPTMTQLNLKYAISGKERARTVGGVSLL
STMTTRQYHQKHLKSIVNTRGASVVIGTTKFYGGWDNMLKNLIDGVENPC
LMGWDYPKCDRALPNMIRMISAMILGSKHTTCCSSTDRFFRLCNELAQVL
TEVVYSNGGFYLKPGGTTSGDATTAYANSVFNIFQAVSANVNKLLSVDSN
VCHNLEVKQLQRKLYECCYRSTTVDDQFVVEYYGYLRKHFSMMILSDDGV
VCYNNDYASLGYVADLNAFKAVLYYQNNVFMSASKCWIEPDINKGPHEFC
SQHTMQIVDKDGTYYLPYPDPSRILSAGVFVDDVVKTDAVVLLERYVSLA
IDAYPLSKHENPEYKKVFYVLLDWVKHLYKTLTAKFWDESFYANMYEKS
3D structure
PDB8g6r An alphacoronavirus polymerase structure reveals conserved co-factor functions.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005524 ATP binding
Biological Process
GO:0006351 DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8g6r, PDBe:8g6r, PDBj:8g6r
PDBsum8g6r
PubMed36993498
UniProtA0A0U2C263

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