Structure of PDB 8g57 Chain A

Receptor sequence
>8g57A (length=109) Species: 8355 (Xenopus laevis) [Search protein sequence]
TKQTARKSTGKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIA
QDFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQ
LARRIRGER
3D structure
PDB8g57 Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
ChainA
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Q5 R40 V46 R63 K64 L65 R69 R83 Q3 R15 V21 R38 K39 L40 R44 R58
BS02 dna A K4 R72 R83 F84 Q85 V117 T118 K2 R47 R58 F59 Q60 V92 T93
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8g57, PDBe:8g57, PDBj:8g57
PDBsum8g57
PubMed37058572
UniProtP84233|H32_XENLA Histone H3.2

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