Structure of PDB 8fzv Chain A

Receptor sequence
>8fzvA (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
GSIALPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALL
LLTKEDFRYRSPHSGDELYELLQHILAQARAAFDLYFVLDKSGSVANNWI
EIYNFVQQLAERFVSPEMRLSFIVFSSQATIILPLTGDRGKISKGLEDLK
RVSPVGETYIHEGLKLANEQIQKAGGLKTSSIIIALTDGKLDGLVPSYAE
KEAKISRSLGASVYAVGVLDFEQAQLERIADSKEQVFPGFQALKGII
3D structure
PDB8fzv Decreasing the flexibility of the TELSAM-target protein linker and omitting the cleavable fusion tag improves crystal order and diffraction limits.
ChainA
Resolution3.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A S92 S94 T158 S92 S94 T158
Gene Ontology
Molecular Function
GO:0043565 sequence-specific DNA binding

View graph for
Molecular Function
External links
PDB RCSB:8fzv, PDBe:8fzv, PDBj:8fzv
PDBsum8fzv
PubMed37747038
UniProtP41212|ETV6_HUMAN Transcription factor ETV6 (Gene Name=ETV6);
P58335|ANTR2_HUMAN Anthrax toxin receptor 2 (Gene Name=ANTXR2)

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