Structure of PDB 8ftq Chain A

Receptor sequence
>8ftqA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
KYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVE
DDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEH
CRKVNEYLNNPPM
3D structure
PDB8ftq A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZTO A M31 L33 V38 C88 F106 W108 M11 L13 V18 C68 F86 W88
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8ftq, PDBe:8ftq, PDBj:8ftq
PDBsum8ftq
PubMed38509117
UniProtQ16186|ADRM1_HUMAN Proteasomal ubiquitin receptor ADRM1 (Gene Name=ADRM1)

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