Structure of PDB 8fta Chain A

Receptor sequence
>8ftaA (length=116) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSPAYLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIK
EPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVFKDANS
IKKIFYMKKAEIEHHE
3D structure
PDB8fta Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16
ChainA
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y8X A L207 F208 K210 P212 Y217 Y220 L255 A259 N263 L32 F33 K35 P37 Y42 Y45 L80 A84 N88
BS02 ZN A H290 E291 H115 E116
Gene Ontology
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0016586 RSC-type complex

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Biological Process
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Cellular Component
External links
PDB RCSB:8fta, PDBe:8fta, PDBj:8fta
PDBsum8fta
PubMed
UniProtQ86U86|PB1_HUMAN Protein polybromo-1 (Gene Name=PBRM1)

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