Structure of PDB 8fr7 Chain A

Receptor sequence
>8fr7A (length=1275) Species: 277944 (Human coronavirus NL63) [Search protein sequence]
ANLSMLQLGVPDNSSTIVTGLLPTHWFCANQSTSVYSANGFFYIDVGNHR
SAFALHTGYYDANQYYIYVTNEIGLNASVTLKICKFSRNTTFDFLSNASS
SFDCIVNLLFTEQLGAPLGITISGETVRLHLYNVTRTFYVPAAYKLTKLS
VKCYFNYSCVFSVVNATVTVNVTTHNGRVVNYTVCDDCNGYTDNIFSVQQ
DGRIPNGFPFNNWFLLTNGSTLVDGVSRLYQPLRLTCLWPVPGLKSSTGF
VYFNATGSDVNCNGYQHNSVVDVMRYNLNFSANSLDNLKSGVIVFKTLQY
DVLFYCSNSSSGVLDTTIPFGPSSQPYYCFINSTINTTHVSTFVGILPPT
VREIVVARTGQFYINGFKYFDLGFIEAVNFNVTTASATDFWTVAFATFVD
VLVNVSATNIQNLLYCDSPFEKLQCEHLQFGLQDGFYSANFLDDNVLPET
YVALPIYYQHTDINFTATASFGGSCYVCKPHQVNISLNGNTSVCVRTSHF
SIRYIYNRVKSGSPGDSSWHIYLKSGTCPFSFSKLNNFQKFKTICFSTVE
VPGSCNFPLEATWHYTSYTIVGALYVTWSEGNSITGVPYPVSGIREFSNL
VLNNCTKYNIYDYVGTGIIRSSNQSLAGGITYVSNSGNLLGFKNVSTGNI
FIVTPCNQPDQVAVYQQSIIGAMTAVNESRYGLQNLLQLPNFYYVSNGGN
NCTTAVMTYSNFGICADGSLIPVRPRNSSDNGISAIITANLSIPSNWTTS
VQVEYLQITSTPIVVDCATYVCNGNPRCKNLLKQYTSACKTIEDALRLSA
HLETNDVSSMLTFDSNAFSLANVTSFGDYNLSSVLPQRNIRSSRIAGRSA
LEDLLFSKVVTSGLGTVDVDYKSCTKGLSIADLACAQYYNGIMVLPGVAD
AERMAMYTGSLIGGMVLGGLTSAAAIPFSLALQARLNYVALQTDVLQENQ
KILAASFNKAINNIVASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQG
SALNHLTSQLRHNFQAISNSIQAIYDRLDSIQADQQVDRLITGRLAALNA
FVSQVLNKYTEVRGSRRLAQQKINECVKSQSNRYGFCGNGTHIFSIVNSA
PDGLLFLHTVLLPTDYKNVKAWSGICVDGIYGYVLRQPNLVLYSDNGVFR
VTSRVMFQPRLPVLSDFVQIYNCNVTFVNISRVELHTVIPDYVDVNKTLQ
EFAQNLPKYVKPNFDLTPFNLTYLNLSSELKQLEAKTASLFQTTVELQGL
IDQINSTYVDLKLLNRFENYIKWPW
3D structure
PDB8fr7 A hinge glycan regulates spike bending and impacts coronavirus infectivity
ChainA
Resolution3.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMA A Y81 Y82 Y59 Y60
Gene Ontology
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046813 receptor-mediated virion attachment to host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0016020 membrane
GO:0019031 viral envelope
GO:0055036 virion membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:8fr7, PDBe:8fr7, PDBj:8fr7
PDBsum8fr7
PubMed
UniProtQ6Q1S2|SPIKE_CVHNL Spike glycoprotein (Gene Name=S)

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