Structure of PDB 8fi3 Chain A

Receptor sequence
>8fi3A (length=307) Species: 573 (Klebsiella pneumoniae) [Search protein sequence]
KDHTIPLTLISILADGEFHSGEQLGEQLGMSRAAINKHIQTLRDWGVDVF
TVPGKGYSLPEPIHLLDEKKISQEIDHGRVTVLPVIDSTNQYLLDRLDEL
TSGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMYWRLEQGPAAAIGLSL
VIGIVIAEVLQQLGAEQVRVKWPNDIYLQDRKLSGILVELTGKTGDAAQI
VSGAGINLVMRGWISLQEAGVVIDRNLLAARLIKELRLGLELFEQEGLAP
YLPRWEKLDNFIHRPVKLIIGDKEIYGISRGIDAQGALLLEQDGVIKAWV
GGEISLR
3D structure
PDB8fi3 Bifunctional ligase/repressor BirA from Klebsiella pneumoniae complexed with biotin (Domain Swapped Dimer)
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.15: biotin--[biotin carboxyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BTN A S89 T90 Q112 G115 R116 G117 R118 W123 K183 G186 I187 L188 G204 A205 G206 S88 T89 Q111 G114 R115 G116 R117 W122 K182 G185 I186 L187 G203 A204 G205
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8fi3, PDBe:8fi3, PDBj:8fi3
PDBsum8fi3
PubMed
UniProtA0A0W7ZMT5

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