Structure of PDB 8fh2 Chain A

Receptor sequence
>8fh2A (length=245) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALHSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRPTSCSRRFYQLTKLLDSVQPIARE
LYQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH
3D structure
PDB8fh2 A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A L705 N706 Q712 M750 F765 T878 L34 N35 Q41 M79 F94 T205
External links
PDB RCSB:8fh2, PDBe:8fh2, PDBj:8fh2
PDBsum8fh2
PubMed36995121
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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