Structure of PDB 8fh0 Chain A

Receptor sequence
>8fh0A (length=241) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACSCSRRFYQLTKLLDSVQPIARELYQL
AFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH
3D structure
PDB8fh0 A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations.
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DHT A L705 N706 Q712 M750 F765 M896 L34 N35 Q41 M79 F94 M219
External links
PDB RCSB:8fh0, PDBe:8fh0, PDBj:8fh0
PDBsum8fh0
PubMed36995121
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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