Structure of PDB 8f7u Chain A

Receptor sequence
>8f7uA (length=236) Species: 9606 (Homo sapiens) [Search protein sequence]
DCGKPQVEPKKCPVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWV
LTAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTRKDIA
LLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGEGLLKEAQLPVI
ENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDAGGPLVCFEKDKYIL
QGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMRNN
3D structure
PDB8f7u Synthesis and structural characterization of new macrocyclicplasmin inhibitors
ChainA
Resolution1.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.7: plasmin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GGI A H603 D646 R719 E724 D735 S736 C737 Q738 T759 S760 W761 G762 G764 C765 H55 D98 R164 E169 D180 S181 C182 Q183 T204 S205 W206 G207 G209 C210
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8f7u, PDBe:8f7u, PDBj:8f7u
PDBsum8f7u
PubMed
UniProtP00747|PLMN_HUMAN Plasminogen (Gene Name=PLG)

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