Structure of PDB 8f6k Chain A

Receptor sequence

>8f6kA (length=279) Species: 70863 (Shewanella oneidensis)

VKLASRASVATALTLITIKLLAWLYSGSASMLASLTDSFADTLASIINFI
AIRYAIVPADHDHRYGHGKAEPLAALAQSAFIMGSAFLLLFYGGERLLNP
SPVENATLGVVVSVVAIVLTLALVLLQKRALAATNSTVVEADSLHYKSDL
FLNAAVLLALVLSQYGWWWADGLFAVLIACYIGQQAFDLGYRSIQALLDR
ELDEDTRQRIKLIAKEDPRVLGLHDLRTRQAGKTVFIQFHLELDGNLSLN
EAASITDTTGLRVKAAFEDAEVIIHQAPV

3D structure

• PDB: 8f6k Characterization of individual Zn2+ binding sites of YiiP
• Chain: A
• Resolution: 3.46 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	A	D47 D51 H155 D159	D37 D41 H145 D149

Gene Ontology

Molecular Function

• GO:0008324 monoatomic cation transmembrane transporter activity
• GO:0015086 cadmium ion transmembrane transporter activity
• GO:0015093 ferrous iron transmembrane transporter activity
• GO:0015341 zinc efflux active transmembrane transporter activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006812 monoatomic cation transport
• GO:0006826 iron ion transport
• GO:0006829 zinc ion transport
• GO:0006882 intracellular zinc ion homeostasis
• GO:0034220 monoatomic ion transmembrane transport
• GO:0034755 iron ion transmembrane transport
• GO:0055085 transmembrane transport
• GO:0070574 cadmium ion transmembrane transport
• GO:0071577 zinc ion transmembrane transport
• GO:0098655 monoatomic cation transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:8f6k, PDBe:8f6k, PDBj:8f6k
• PDBsum: 8f6k
• PubMed: 37906094
• UniProt: Q8E919|FIEF_SHEON Cation-efflux pump FieF (Gene Name=fieF)