Structure of PDB 8f3s Chain A

Receptor sequence
>8f3sA (length=640) Species: 1352 (Enterococcus faecium) [Search protein sequence]
TQAVEAGEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQ
NIYGAADVKGLQISNLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTL
DRNDGQTTINWQPNLVFPEMEGNDKVSLTTQEAARGNIIDRNGEPLATTG
KLKQLGVVPSKLGDGGEKTANIKAIASSFDLTEDAINQAISQSWVQPDYF
VPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIGYVGDITAEDIDK
NPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIEHEVQ
NGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPN
KMTNGISQEDYKAYEENPEQPFISRFATGYAPGSTFKMITAAIGLDNGTI
DPNEVLTINGLKWQKDSSWGSYQVTRVSDVSQVDLKTALIYSDNIYMAQE
TLKMGEKKFRIGLDKFIFGEDLDLPISMNPAQISNEDSFNSDILLADTGY
GQGELLINPIQQAAMYSVFANNGTLVYPKLIADKETKDKKNVIGETAVQT
IVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEIKEKQDVKGKENSFLF
AFNPDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ
3D structure
PDB8f3s The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PNM A S422 V465 S480 N482 T618 G619 T620 S384 V427 S442 N444 T580 G581 T582
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0071972 peptidoglycan L,D-transpeptidase activity
Biological Process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8f3s, PDBe:8f3s, PDBj:8f3s
PDBsum8f3s
PubMed
UniProtG5CKR9

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