Structure of PDB 8f3g Chain A

Receptor sequence
>8f3gA (length=624) Species: 1352 (Enterococcus faecium) [Search protein sequence]
TQAVEAGEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQ
NIYGAADVKGLQISNLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTL
DRNDGQTTINWQPNLVFPEMEGNDKVSLTTQEAARGNIIDRNGEPLATTG
KLKQLLGDGGEKTANIKAIASSFDLTEDAINQAISQSWVQPDYFVPLKII
ELPAEVDGRYYPLGEAAAQLIGYVGDITAEDIDKNPELSSNGKIGRSGLE
MAFDKDLRGTTGGKLSITDADGVEKKVLIEHEVQNGKDIKLTIDAKAQKT
AFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTNGISQEDYKAYEE
NPEQPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLKWQKD
SSWGSYQVTRVSDVSQVDLKTALIYSDNIYMAQETLKMGEKKFRTGLDKF
IFGEDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMY
SVFANNGTLVYPKLIADKETKDKKNVIGETAVQTIVPDLREVVQDVNGTA
HSLSALGIPLAAKTGTAEIKEKQDVKGKENSFLFAFNPDNQGYMMVSMLE
NKEDDDSATKRASELLQYLNQNYQ
3D structure
PDB8f3g The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
ChainA
Resolution3.59 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PNM A S422 V465 S480 N482 T618 G619 T620 E622 S368 V411 S426 N428 T564 G565 T566 E568
Gene Ontology
Molecular Function
GO:0008658 penicillin binding
GO:0071972 peptidoglycan L,D-transpeptidase activity
Biological Process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8f3g, PDBe:8f3g, PDBj:8f3g
PDBsum8f3g
PubMed
UniProtG5CKR9

[Back to BioLiP]