Structure of PDB 8f15 Chain A

Receptor sequence
>8f15A (length=133) Species: 9606 (Homo sapiens) [Search protein sequence]
GASPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCY
LKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA
YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEER
3D structure
PDB8f15 Single-Shot Flow Synthesis of D-Proteins for Mirror-Image Phage Display
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K30 N34 V61 N65 K95 F98 Q102 L105 F131 D134 I135 S137 A138 K10 N14 V41 N45 K75 F78 Q82 L85 F111 D114 I115 S117 A118
BS02 peptide A R51 T54 R55 R31 T34 R35
BS03 WHL A N34 F37 V38 K72 N14 F17 V18 K52
External links
PDB RCSB:8f15, PDBe:8f15, PDBj:8f15
PDBsum8f15
PubMed
UniProtQ9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)

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