Structure of PDB 8exw Chain A

Receptor sequence
>8exwA (length=779) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
EDEDPTPYLFVSLEQRRIDQSKPYDSKKSCWIPDEKEGYLLGEIKATKGD
IVSVGLQGGETRDLKKDLLQQVNPPKYEKAEDMSNLTYLNDASVLHNLRQ
RYYNKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPPHIFAI
SDGAYVDMLTNHVNQSMLITGESGAGKTENTKKVIAYFATVGASKGSLED
QVVQTNPVLEAFGNAKTVRNDNSSRFGKFIRIHFGPTGKLAGADIETYLL
EKARVISQQSLERSYHIFYQIMSGSVPGVKEMCFLSDNIYDYYNVSQGKV
TVPNMDDGEEFQLADQAFDILGFTKQEKEDVYRITAAVMHMGGMKFKQRG
REEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQ
QVTNSIGALCKGVFDRLFKWLVKKCNETLDTQQKRQHFIGVLDIAGFEIF
EYNGFEQLCINFTNEKLQQFFNHIMFVMEQEEYKKEGINWDFIDFGMDLL
ACIDLIEKPMGILSILEEESMFPKATDQTFSEKLTNTHLGKSAPFQKPKP
PKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKLL
IEIFADHAGQKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMK
QPGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYMILAPAI
MAAEKVAKNAAGKCLEAVGLDPDMYRIGHTKVFFRAGVLGQMEEFRDERL
GKIMSWMQAWARGYLSRKGFKKLQEQRVA
3D structure
PDB8exw Drosophila melanogaster indirect flight muscle myosin II (subfragment-1)
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A T186 S241 T178 S224
BS02 ADP A N127 P128 G182 G184 K185 T186 E187 N237 N119 P120 G174 G176 K177 T178 E179 N220
Gene Ontology
Molecular Function
GO:0003774 cytoskeletal motor activity
GO:0005524 ATP binding
GO:0051015 actin filament binding
Cellular Component
GO:0016459 myosin complex

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8exw, PDBe:8exw, PDBj:8exw
PDBsum8exw
PubMed
UniProtP05661|MYSA_DROME Myosin heavy chain, muscle (Gene Name=Mhc)

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