Structure of PDB 8esa Chain A

Receptor sequence
>8esaA (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGCYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTELVETRPAGDGTFQKWAAVVVPSGQ
EQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB8esa Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159 Y7 E63 K66 H70 D77 C84 Y99 Y123 T143 V152 Y159
Gene Ontology
Biological Process
GO:0006955 immune response
Cellular Component
GO:0042612 MHC class I protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:8esa, PDBe:8esa, PDBj:8esa
PDBsum8esa
PubMed37100770
UniProtP61769|B2MG_HUMAN Beta-2-microglobulin (Gene Name=B2M);
Q53Z42

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