Structure of PDB 8eni Chain A

Receptor sequence
>8eniA (length=321) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
SKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLKLEGCKID
SVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKS
LVGNQSSFFILSDEQTKGRGRFNRHWSSKGQGLWMSVVLRPNVAFSMISK
FNLFIALGIRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDGI
EAIICGIGINLTQQLENFDESIRHRATSIQLHDKNKLDRYQFLERLLQEI
EKRYNQFLTLPFSEIREEYIAASNIWNRTLLFTENDKQFKGQAIDLDYDG
YLIVRDEAGESHRLISADIDF
3D structure
PDB8eni Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.4.15: biotin--[biotin carboxyl-carrier protein] ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WNE A S93 T94 Q95 Q116 G119 R120 G121 R122 H126 W127 K187 F191 G208 I209 G210 I224 A228 S92 T93 Q94 Q115 G118 R119 G120 R121 H125 W126 K185 F189 G206 I207 G208 I222 A226
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004077 biotin--[biotin carboxyl-carrier protein] ligase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0016874 ligase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8eni, PDBe:8eni, PDBj:8eni
PDBsum8eni
PubMed29131575
UniProtA0A0H3JRH8

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