Structure of PDB 8ek5 Chain A

Receptor sequence
>8ek5A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQMMFG
CDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKWEAA
HVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB8ek5 Structural principles of peptide-centric Chimeric Antigen Receptor recognition guide therapeutic expansion.
ChainA
Resolution2.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y8 E64 K67 V68 A70 H71 T74 N78 I81 Y85 F100 Y117 Y124 T144 K147 W148 Y160 Y172 Y7 E63 K66 V67 A69 H70 T73 N77 I80 Y84 F99 Y116 Y123 T143 K146 W147 Y159 Y171
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