Structure of PDB 8eic Chain A

Receptor sequence
>8eicA (length=516) Species: 9606 (Homo sapiens) [Search protein sequence]
ATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAI
VRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPV
DSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITT
DCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLS
VCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGM
EGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALV
RTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLL
HPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQ
RRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPL
FVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRN
EGVATYAAAVLFRMSE
3D structure
PDB8eic Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
ChainA
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R474 R515 L519 R582 R612 T653 Y654 A656 A657 R326 R367 L371 R434 R464 T505 Y506 A508 A509
BS02 WHL A E620 Q623 E472 Q475
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

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Molecular Function
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Biological Process
External links
PDB RCSB:8eic, PDBe:8eic, PDBj:8eic
PDBsum8eic
PubMed37914719
UniProtP35222|CTNB1_HUMAN Catenin beta-1 (Gene Name=CTNNB1)

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