Structure of PDB 8ehz Chain A

Receptor sequence
>8ehzA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
KSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYL
KMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAY
SLAKEQRLNFGDDIPSALRIAKKKRWNSI
3D structure
PDB8ehz Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides
ChainA
Resolution2.06 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K30 N34 N65 K72 K95 F98 F99 F131 D134 K9 N13 N44 K51 K74 F77 F78 F110 D113
External links
PDB RCSB:8ehz, PDBe:8ehz, PDBj:8ehz
PDBsum8ehz
PubMed37914719
UniProtQ9UNE7|CHIP_HUMAN E3 ubiquitin-protein ligase CHIP (Gene Name=STUB1)

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