Structure of PDB 8eh0 Chain A

Receptor sequence
>8eh0A (length=385) Species: 2336 (Thermotoga maritima) [Search protein sequence]
GNFGPYGGQNVPEILMGALEELEAAYEGIMKDESFWKEYNDLLRDYAGRP
TPLYFARRLSEKYGARVYLKREDLLHTGAHKINNAIGQVLLAKLMGKTRI
TAGTGAGQHGVATATAAALFGMECVIYMGEEDTIRQKLNVERMKLLGAKV
VPVKSGSRTLKDAIDEALRDWITNLQTTYYVPGSVVGPHPYPIIVRNFQK
VIGEETKKQIPEKEGRLPDYIVACVSGGSNAAGIFYPFIDSGVKLIGVEA
GGEGLETGKHAASLLKGKIGYLHGSKTFVLQDDWGQVQASHSVSAGLDYP
GVGPEHAYWRETGKVLYDAVTDEEALDAFIELSRLEGIIPALESSHALAY
LKKINIKGKVVVVNLSGRGDKDLESVLNHPYVRER
3D structure
PDB8eh0 Towards automated crystallographic structure refinement with phenix.refine.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.1.20: tryptophan synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0JO A H82 K83 T106 G107 A108 Q110 H111 S186 G230 S231 N232 G298 E345 S368 G369 H80 K81 T104 G105 A106 Q108 H109 S184 G228 S229 N230 G296 E343 S366 G367
BS02 QOX A L162 I166 Y182 P184 G185 S186 V188 Y301 L160 I164 Y180 P182 G183 S184 V186 Y299
Gene Ontology
Molecular Function
GO:0004834 tryptophan synthase activity
GO:0016829 lyase activity
Biological Process
GO:0000162 tryptophan biosynthetic process
GO:0006568 tryptophan metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8eh0, PDBe:8eh0, PDBj:8eh0
PDBsum8eh0
PubMed38744987
UniProtP50909|TRPB1_THEMA Tryptophan synthase beta chain 1 (Gene Name=trpB1)

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