Structure of PDB 8egn Chain A

Receptor sequence
>8egnA (length=309) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HHHHHMRRIHFVGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKF
GAQIFIGHQAENADGADVLVVSSAINRANPEVASALERRIPVVPRAEMLA
ELMRYRHGIAVAGTHGKTTTTSLIASVFAAGGLDPTFVIGGRLNAAGTQL
GASRYLVAEADESDASFLHLQPMVAVVTNIDADHMATYGGDFNKLKKTFV
EFLHNLPFYGLAVMCVDDPVVREILPQIARPTVTYGLSEDADVRAINIRQ
EGMRTWFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIV
QGLSGFQGV
3D structure
PDB8egn Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.8: UDP-N-acetylmuramate--L-alanine ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WIR A H117 G118 T182 N183 C219 Y239 H281 L284 N285 H115 G116 T178 N179 C215 Y235 H277 L280 N281
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8egn, PDBe:8egn, PDBj:8egn
PDBsum8egn
PubMed
UniProtQ9HW02|MURC_PSEAE UDP-N-acetylmuramate--L-alanine ligase (Gene Name=murC)

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