Structure of PDB 8egm Chain A

Receptor sequence
>8egmA (length=303) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MRRIHFVGIGGAGMCGIAEVLLNLGYEVSGSDLKASAVTERLEKFGAQIF
IGHQAENADGADVLVVSSARANPEVASALERRIPVVPRAEMLAELMRYRH
GIAVAGTHGKTTTTSLIASVFAAGGLDPTFVIGGRLNAAGTNAQLGASRY
LVAEADESDASFLHLQPMVAVVTNIDADHMATYGGDFNKLKKTFVEFLHN
LPFYGLAVMCVDDPVVREILPQIARPTVTYGLSEDADVRAINIRQEGMRT
WFTVLRPEREPLDVSVNMPGLHNVLNSLATIVIATDEGISDEAIVQGLSG
FQG
3D structure
PDB8egm Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.8: UDP-N-acetylmuramate--L-alanine ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 WIU A G125 T189 N190 D229 Y246 H288 L291 N292 G109 T173 N174 D213 Y230 H272 L275 N276
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008763 UDP-N-acetylmuramate-L-alanine ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0009058 biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8egm, PDBe:8egm, PDBj:8egm
PDBsum8egm
PubMed
UniProtQ9HW02|MURC_PSEAE UDP-N-acetylmuramate--L-alanine ligase (Gene Name=murC)

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