Structure of PDB 8ebm Chain A

Receptor sequence
>8ebmA (length=323) Species: 9606 (Homo sapiens) [Search protein sequence]
ACPAERSGHVAVSDGRHMFVWGGYKSNFYLPREELWIYNMETGRWKKINT
EGDVPPSMSGSCAVCVDRVLYLFGGHHSRGNTNKFYMLDSRRVLQWERID
CQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSS
HPRGWNDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGR
YRDARMNDLHYLNLDTWEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGG
FTTDKQPLSDAWTYCISKNEWIQFNHPYTEKPRLWHTACASDEGEVIVFG
GCANNLLVHHRAAHSNEILIFSV
3D structure
PDB8ebm E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity.
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y50 S92 H109 K147 Y163 R189 W191 R236 R241 S269 W270 H345 Y24 S59 H76 K111 Y127 R153 W155 R200 R205 S233 W234 H309
External links
PDB RCSB:8ebm, PDBe:8ebm, PDBj:8ebm
PDBsum8ebm
PubMed36805027
UniProtQ9Y2U9|KLDC2_HUMAN Kelch domain-containing protein 2 (Gene Name=KLHDC2)

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