Structure of PDB 8eb2 Chain A

Receptor sequence
>8eb2A (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB8eb2 HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171 Y7 E63 K66 H70 T73 D77 L81 Y84 R97 Y99 T143 K146 W147 Q155 Y159 W167 Y171
BS02 peptide A H191 D196 S251 E254 W274 E275 H191 D196 S251 E254 W274 E275
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