Structure of PDB 8ea8 Chain A

Receptor sequence
>8ea8A (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
ESYCGPCPKNWICYKNNCYQFFDEEKNWYESQASCMSQNASLLKVYSKED
QDLLKLVKSYHWMGLVHIPGSWQWEDGSSLSPNLLTIIEMQKGDCALYAS
SFKGYIENCSTPNTYICMQR
3D structure
PDB8ea8 Identification of small-molecule protein-protein interaction inhibitors for NKG2D.
ChainA
Resolution1.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VML A I104 F113 L148 V149 K150 I210 I12 F21 L56 V57 K58 I116
Gene Ontology
Biological Process
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity

View graph for
Biological Process
External links
PDB RCSB:8ea8, PDBe:8ea8, PDBj:8ea8
PDBsum8ea8
PubMed37098070
UniProtP26718|NKG2D_HUMAN NKG2-D type II integral membrane protein (Gene Name=KLRK1)

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