Structure of PDB 8e9a Chain A

Receptor sequence
>8e9aA (length=175) Species: 10498 (African swine fever virus BA71V) [Search protein sequence]
SMLTLIQGKKIVNHLRSRLAFEYNGQLIKILSKNIVAVGSLRREEKMLND
VDLLIIVPEKKLLKHVLPNIRIKGLSFSVKVCGERKCVLFIEWEKKTYQL
DLFTALAEEKPYAIFHFTGPVSYLIRIRAALKKKNYKLNQYGLFKNQTLV
PLKITTEKELIKELGFTYRIPKKRL
3D structure
PDB8e9a Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation.
ChainA
Resolution2.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A D49 D51 C81 G82 E83 R84 K85 H115 F116 G118 V120 I124 R127 K131 K136 Y140 D50 D52 C82 G83 E84 R85 K86 H116 F117 G119 V121 I125 R128 K132 K137 Y141
BS02 MG A D49 D51 D50 D52
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8e9a, PDBe:8e9a, PDBj:8e9a
PDBsum8e9a
PubMed37301907
UniProtP42494|DPOLX_ASFB7 Repair DNA polymerase X (Gene Name=Ba71V-97)

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