Structure of PDB 8e8w Chain A

Receptor sequence
>8e8wA (length=452) Species: 285532 (Streptomyces achromogenes subsp. streptozoticus) [Search protein sequence]
VPPHVPFELSGAELRDAIVQYATNPIYHDNLDWLNHDNPYRRQLRPQVLP
HLDYDKVPGRENILNYASLAVQRLLTSVYEADLVFFPKSGLKGKEEDFRA
FYSPANRALGERIRPALERYAFGFLDDEVGTWTAQSLDAYLDSLEQSPVE
KAILGSADRERAARMWLVQFAPDFLSEASPMMRNVLGYYGPAQSEWFKVV
IDEYGGVHDTKHSTLFERTLESVGLESDLHRYWQYYLNSSLLLNNYFHYL
GKNHELFFRYVGALYYTESSLVDFCRRADHLLREVFGDTVDTTYFTEHIH
GRMAREKIIKPLVEAHGDGIIPEIVRGIEEYRVLLEIGDFDFSEQIAWMD
AQPELKKLHDPVFEGLKQGKVAPVAHLVEPRGELSNTHCHDGDELCHIVS
GTMRFESGLGSSLTLQAGEGVVIKRNRLHGANIESDECVYEIHSVGDYRK
CL
3D structure
PDB8e8w Crystal structure of SznF from Streptomyces achromogenes var. streptozoticus NRRL 2697 mononuclear Fe(II) structure on the HDO cofactor assembly pathway
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.13.250: nitrosourea synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE2 A E189 E215 H225 H311 E177 E203 H212 H298
BS02 FE2 A H407 H409 H448 H388 H390 H429
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:8e8w, PDBe:8e8w, PDBj:8e8w
PDBsum8e8w
PubMed
UniProtA0A411MR89|SZNF_STRC2 Nitrosourea synthase (Gene Name=sznF)

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