Structure of PDB 8e7f Chain A

Receptor sequence
>8e7fA (length=614) Species: 615 (Serratia marcescens) [Search protein sequence]
YQDPGRLGAPDSWKTAEFNRQWGLEAISAEFAYARGYTGKGITIGVIDNA
ILSHSEFSGKLTRLDNGSYNFSYDKQDNMSFGDHGTHVAGIAAAKRDGAG
MHGVAFDADIIGTKLNDYGNRNGREELIQSAARVINNSWGIAPDIRRDAK
GDIIWLPNGRPDYVAFVKSEVIAEMMRSKSSVEWGSEQPVPTGGHSAMST
LLRAARHGKLIVFSAGNYNNYNIPEAQKSLPYAFPDVLNNYLIVTNLSDE
NQLSVSSTSCGQTASYCVSAPGSDIYSTVGRLESNTGGAVNREAYNKGEL
SLNPGYGNKSGTSMAAPHVTGVAAVLMQRFPYMSADQISAVIKTTATDLG
VAGIDNLFGWGRVNLRDAINGPKMFITKEDIPQEYYVPGSYSEKQFVVNI
PGLGNIVEPGTPVERRCTSSECSFDSWSNDISGHGGLTKTGAGTLALLGN
NTYRGDTWVKQGVLAIDGSVASNVYIENSGTLSGEGTVGAFRAARSGSVA
PGNGIGTLHVLHDAIFDRGSQYNVEVADNGRSDKIAARRAFLNGGSVNVS
LERSQNLLSQNEAQSLLGNKYTILTTTDGVTGRFENANPSYPFVKVALDY
RGNDVGLGITRTDA
3D structure
PDB8e7f Crystal structure of a subtilisin-like autotransporter passenger domain reveals insights into its cytotoxic function.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D376 L377 V379 G381 D383 D348 L349 V351 G353 D355
BS02 CA A E45 E84 K123 D125 A127 M129 E17 E56 K95 D97 A99 M101
BS03 CA A P529 G532 E553 D561 P501 G504 E525 D533
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:8e7f, PDBe:8e7f, PDBj:8e7f
PDBsum8e7f
PubMed36859523
UniProtP09489|PRTS_SERMA Extracellular serine protease

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