Structure of PDB 8e67 Chain A

Receptor sequence
>8e67A (length=93) Species: 10090 (Mus musculus) [Search protein sequence]
IADSRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHK
NRTNMTYEKMSRALRYYYKLNIIRKEPGQRLLFRFMKTPDEIM
3D structure
PDB8e67 The functional role of histidine within the ETV6 ETS domain
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R392 R395 Y396 Y398 L411 R62 R65 Y66 Y68 L81
BS02 dna A L336 L337 W376 K380 R382 M385 K389 R392 Y396 Y397 L6 L7 W46 K50 R52 M55 K59 R62 Y66 Y67
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8e67, PDBe:8e67, PDBj:8e67
PDBsum8e67
PubMed
UniProtP97360|ETV6_MOUSE Transcription factor ETV6 (Gene Name=Etv6)

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