Structure of PDB 8e1v Chain A

Receptor sequence
>8e1vA (length=330) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
NVVGICAMDAKARSKPCRNILNRIIAEGEFEAIVFGDNMILDEAVENWPA
CDYLICFYSSGFPLKKAEKYVELRKPFCVNDVVFQELLWDRRLVLNILDA
IRVSTPQRLICSRDGGPKINKVLEEKLRRKFGIEITEVPTPEVKMLDEDT
LSVDGKIIKKPYVEKPVYGEDHNIYIYFPKSVGGGGRKLFRKVANKSSDY
DPDLCAPRTEGSFIYEEFMNVDNAEDVKVYTVGPHYSHAETRKSPVVDGI
VRRNPHGKEIRFITNLSEEEKNMASKISIAFEQPVCGFDLLRVSGQSYVI
DVNGWSFVKDNNDYYDNAARILKQMFHVAE
3D structure
PDB8e1v Structures of Fission Yeast Inositol Pyrophosphate Kinase Asp1 in Ligand-Free, Substrate-Bound, and Product-Bound States.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.24: diphosphoinositol-pentakisphosphate 1-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A R123 V195 K197 H204 I206 L221 E248 F250 M251 D258 D321 L323 I332 D333 N335 R91 V163 K165 H172 I174 L189 E216 F218 M219 D226 D289 L291 I300 D301 N303
BS02 MG A D321 D333 D289 D301
BS03 IHP A K43 K224 K260 R274 K290 R293 K341 K11 K192 K228 R242 K258 R261 K309
Gene Ontology
Molecular Function
GO:0000829 diphosphoinositol pentakisphosphate kinase activity

View graph for
Molecular Function
External links
PDB RCSB:8e1v, PDBe:8e1v, PDBj:8e1v
PDBsum8e1v
PubMed36468882
UniProtO74429|VIP1_SCHPO Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase (Gene Name=asp1)

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