Structure of PDB 8e1d Chain A

Receptor sequence
>8e1dA (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
GSATQSPGDSRRLSIQRAIQSLVHAAQCRNANCSLPSCQKMKRVVQHTKG
CKRKTNGGCPICKQLIALAAYHAKHCQENKCPVPFCLNIKQK
3D structure
PDB8e1d Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor.
ChainA
ResolutionN/A
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H1744 C1748 C1753 C1758 H24 C28 C33 C38
BS02 ZN A H1767 C1771 C1779 C1782 H47 C51 C59 C62
BS03 ZN A H1792 C1796 C1801 C1806 H72 C76 C81 C86
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8e1d, PDBe:8e1d, PDBj:8e1d
PDBsum8e1d
PubMed37353163
UniProtQ09472|EP300_HUMAN Histone acetyltransferase p300 (Gene Name=EP300)

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