Structure of PDB 8e0x Chain A

Receptor sequence
>8e0xA (length=344) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
YQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIHKILKGNDD
RLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQY
LADLMSWGAIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINA
AGAPHCFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEG
LNKAGLPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVE
SHLVEGNQSLEPLAYGKSITDACIGWEDTDALLRQLANAVKARR
3D structure
PDB8e0x Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation.
ChainA
Resolution1.97 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.5.1.54: 3-deoxy-7-phosphoheptulonate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A C61 H268 E302 D326 C59 H266 E300 D321
BS02 PEP A R92 Y94 P98 E143 K186 R234 H268 R90 Y92 P96 E141 K184 R232 H266
Gene Ontology
Molecular Function
GO:0003849 3-deoxy-7-phosphoheptulonate synthase activity
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009073 aromatic amino acid family biosynthetic process
GO:0009423 chorismate biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8e0x, PDBe:8e0x, PDBj:8e0x
PDBsum8e0x
PubMed36197914
UniProtP0AB91|AROG_ECOLI Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (Gene Name=aroG)

[Back to BioLiP]