Structure of PDB 8dwm Chain A

Receptor sequence
>8dwmA (length=248) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKTNDYRPVQDLREVNKRVEDIH
PTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPS
GQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAA
TSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
3D structure
PDB8dwm Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.
ChainA
Resolution2.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A Y64 R116 Y41 R90
BS02 dna A L99 D114 R116 G191 L76 D88 R90 G161
External links
PDB RCSB:8dwm, PDBe:8dwm, PDBj:8dwm
PDBsum8dwm
PubMed36516684
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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