Structure of PDB 8dvg Chain A

Receptor sequence
>8dvgA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWELS
3D structure
PDB8dvg Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.
ChainA
Resolution2.594 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 E152 Y159 W167 Y171 Y7 E63 N66 D77 Y84 Y99 D116 T143 K146 W147 E152 Y159 W167 Y171
External links
PDB RCSB:8dvg, PDBe:8dvg, PDBj:8dvg
PDBsum8dvg
PubMed37604828
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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