Structure of PDB 8dtc Chain A

Receptor sequence
>8dtcA (length=374) Species: 5755 (Acanthamoeba castellanii) [Search protein sequence]
LVDIGEEARPALLHWKDRFKESLKYFVGVDIGGTNTRVALDTGSSDEPYV
QIAKFRASSSKHIVEGLQQVARQVADILGVPASGACLAGAGRIGDDGLSL
DITNYPGTPADRTLTSDQLPTYLFPADATHYINDLESTCYGLKSLNESNQ
LASFFKPLWSTSDTVTMKRANYLVLAVGTGLGIALLTSLGRGSRNIPLQV
MPMEFGHALYSPVTDPAKKDEEDRLAAYLSKTLYSGKNAIEYEDIVSGRG
VLAVYQWITAEHKEAAKYESAEEISAAAFREDPCPFATKALLIHYRFLMR
VAKNLCVGLQAKGMFLAGDNQVVNNPFFEKYLAEMRAEFLDHPKPDWIDK
VELYTQTQSFNINLHGALYYARTD
3D structure
PDB8dtc Crystal Structure of Glucokinase with bound glucose from Acanthamoeba castellanii
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BGC A G102 T114 N144 D145 L192 G193 E215 H218 E254 G91 T103 N133 D134 L181 G182 E204 H207 E243
BS02 BGC A G43 G44 T45 N46 R48 G32 G33 T34 N35 R37
Gene Ontology
Molecular Function
GO:0004340 glucokinase activity
GO:0005524 ATP binding
GO:0005536 D-glucose binding
Biological Process
GO:0006096 glycolytic process
GO:0051156 glucose 6-phosphate metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8dtc, PDBe:8dtc, PDBj:8dtc
PDBsum8dtc
PubMed
UniProtL8GT25

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